Histaminergic neurotransmission as a gateway for the effects of the fat sensing molecule Oleoylethanolamide

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Costa, A.; 2019; Histaminergic neurotransmission as a gateway for the effects of the fat sensing molecule Oleoylethanolamide. Firenze, Firenze University Press.


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Histaminergic neurotransmission as a gateway for the effects of the fat sensing molecule Oleoylethanolamide

Focus on cognition and stress-reactivity

Alessia Costa
ORCID: 0000-0002-3693-3019

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DOI: 10.36253/978-88-6453-995-9 Series: Premio Tesi di Dottorato ISSN 2612-8039 (print) - ISSN 2612-8020 (online)

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© 2019 Author(s)
Published by Firenze University Press

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Metadata licence CC0 1.0

The histaminergic system is a pleiotropic system that commands general states of metabolism and consciousness, including learning and memorizing both pleasurable and aversive events. Brain histamine mediates the central effects of a signal molecule produced in the intestine, namely oleoylethanolamide (OEA). OEA is released by the enterocytes in response to high fat intake and reduces eating, by indirectly activating a subpopulation of histaminergic neurons. In her thesis, she explored other potential interactions between these two systems in the pursuit of unexplored neuronal mechanisms that may shed light on the mode of action of psychoactive agents and possibly lead to the development of new drugs.

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Publication year: 2019

Price: 11,90 €

Pages: 124

ISSN print: 2612-8039

ISBN: 978-88-6453-994-2

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Publication year: 2019

Pages: 124

ISSN online: 2612-8020

e-ISBN: 978-88-6453-995-9

DOI: 10.36253/978-88-6453-995-9

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© 2019 Author(s)
Content licence CC BY 4.0
Metadata licence CC0 1.0

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Publication year: 2019

ISSN online: 2612-8020

e-ISBN: 978-88-9273-018-2

DOI: 10.36253/978-88-6453-995-9

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© 2019 Author(s)
Content licence CC BY 4.0
Metadata licence CC0 1.0